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Sotio

Sotio Biotech

SOTIO Biotech Group, operating within the PPF Biotech arm, researches and develops innovative cancer treatments and applies its scientific immunotherapy knowledge to clinical trials. Teams of leading experts from all over the world work for SOTIO as part of its extensive international activities. 

SOTIO, part of PPF Group since 2012, coordinates the Group’s biotechnology activities. It is building a diversified portfolio of immuno-oncology programmes based on in-house research and development, partnerships, licensing agreements, investments, mergers, and acquisitions. It has operations in Europe and the US, with principal centres in Prague, Basel, and Boston. SOTIO Group, which has its own scientific and laboratory facilities in Prague, is the largest privately funded research endeavour in the Czech Republic.

Sotio

SOTIO’s research and development programmes embrace next-generation antibody-drug conjugate (ADC) oncology products, personalised cellular immunotherapy on the CAR-T platform, and IL–15 superagonist-based treatments, including immunocytokines. 

SOTIO has been validating the safety and efficacy of its products in comprehensive clinical trials conducted in Europe and the US since 2012.  

In July 2024, SOTIO entered into a multi-target antibody agreement with Biocytogen. This option and licence agreement includes multiple fully human bispecific antibodies developed using with Biocytogen’s proprietary platform. The agreement enables SOTIO to significantly broaden its next-generation ADC portfolio, including multi-specific ADCs.

Other PPF Biotech Holdings

Autolus Therapeutics

Autolus Therapeutics is a leader in the development of treatments based on CAR-T cells (genetically engineered T cells). The company is dedicated to the clinical development of a wide portfolio of next-generation T-cell therapies targeting both hematological and solid tumors. www.autolus.com     

Cellestia Biotech

Cellestia Biotech was founded in 2014 as a spin-off of the Swiss Federal Institute of Technology Lausanne (EPLF). Cellestia’s lead development compound is CB-103, a novel, first-in-class oral pan-NOTCH inhibitor with an innovative mode of action meant for the treatment of patients with NOTCH-driven lymphomas and solid tumors. www.cellestia.com
Sotio Biotech

"SOTIO exemplifies the world-class standard of Czech science in its mission and results. Our efforts are focused on finding a cure for cancer."

Radek Špíšek

CEO, SOTIO Biotech

Contacts

SOTIO Biotech a.s.

​​​​​​​Českomoravská 2532/19b
190 00 Prague 9
Czech Republic

Sotio Biotech B.V.

Zuidplein 168
1077 XV Amsterdam
The Netherlands

PPF Biotech B.V.

Zuidplein 168
1077 XV Amsterdam
The Netherlands